Unlocking the Power of the Estrobolome:
How Your Microbiome Influences Your Hormones

We hope this newsletter finds you in good health and high spirits after a well-lived summer. We know summer has been full of Colorado adventures for us, and now as the air feels a little crisper in the mornings it is the perfect time to refocus on getting our internal health in order. Today, we dive into a fascinating topic that highlights the intricate connection between our gut microbiome and overall health: the Estrobolome, A Microbiome Marvel.

The Estrobolome is an intriguing subset of our gut microbiome that plays a vital role in estrogen metabolism. Estrogen, the hormone primarily associated with female reproductive health, comes in various forms, including estradiol, estriol, and estrone. Maintaining a healthy balance of these hormones is crucial for overall well-being.

The Role of Beta-Glucuronidase
One key player in this intricate dance is an enzyme called beta-glucuronidase. When our bodies process estrogen, the liver attaches a molecule called glucuronic acid to estrogen molecules, making them water-soluble and easier to excrete. However, certain gut bacteria produce beta-glucuronidase, an enzyme that has the opposite effect. Beta-glucuronidase can cause estrogen molecules more likely to be reabsorbed into the body. When the bacteria in our gut are unhealthy and out of balance, it allows for more beta-glucuronidase, which is why taking care of your intestinal health is important.

The Consequences of High Estrogen
So, why is it bad to have high estrogen levels? High estrogen dominance, can lead to several health issues, including:

  • Breast Cancer, Uterine Fibroids, Endometriosis a painful condition where uterine tissue grows outside the uterus, weight gain particularly around the hips and thighs, and irregular/heavy menstrual cycles.

Maintaining Your Estrobolome’s Balance
To support a healthy estrobolome and balanced estrogen metabolism, consider implementing the following in your daily health practices:

  • Diet: Opt for a diet rich in fiber, prebiotics, and fermented foods to promote a diverse and balanced gut microbiome.
  • Probiotics: Consider probiotic supplements with strains that support estrogen metabolism, such as Lactobacillus and Bifidobacterium species.
  • Lifestyle: Manage stress, engage in regular exercise, and limit excessive alcohol consumption, as these factors can influence the gut microbiome and estrogen metabolism.
  • Work with a qualified Holistic Practitioner for an individualized approach if you suspect estrogen dominance or related health issues.

Understanding the role of the Estobolome in estrogen metabolism underscores the importance of a healthy gut microbiome in maintaining hormonal balance and overall health. By taking proactive steps to support your Estrobolome, and understanding that gut health IS health you are setting yourself up for long-term health.

Thank you for being part of our Holistica community, and stay tuned for more enlightening insights into health and well-being!

In Health,
Dr. Sulser and the Holistica Team.